Calcitriol and the parathyroid hormone-ionized calcium curve: a comparison of methodologic approaches.

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Calcitriol and the parathyroid hormone-ionized calcium curve: a comparison of methodologic approaches.

Investigations of the effects of calcitriol on the inverse sigmoidal relationship between parathyroid hormone (PTH) and ionized calcium (iCa) have yielded contradictory conclusions, possibly because of variations in experimental and analytical approaches. To clarify the existing literature, PTH-iCa curves were constructed by inducing hypo- and hypercalcemia through alterations in dialysate calc...

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The Set Point of Intact Parathyroid Hormone-Ionized Calcium Curve during the Progression of Secondary Hyperparathyroidism among Patients Undergoing Haemodialysis

The parathyroid gland secretes parathyroid hormone (PTH) which is a key element in the regulation of serum calcium. The PTH elevates serum calcium activities by regulating its action on the bones, kidneys and small intestine. The set point of PTH secretion defines the sensitivity of the parathyroid glands to calcium concentration. Secondary hyperparathyroidism (SHPT) is a common complication of...

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Assessment of calcium balance in patients on hemodialysis, based on ionized calcium and parathyroid hormone responses.

BACKGROUND Identification of the underlying causes of secondary hyperparathyroidism (SHPT) in individual patients on hemodialysis (HD) is hampered by the lack of clinically reliable information on calcium balance. The aim of this study was to assess calcium balance during HD sessions with a method that is applicable in day-to-day practice. METHODS Plasma ionized calcium (pCa2+) and parathyroi...

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The acute effect of chlorothiazide on serum-ionized calcium. Evidence for a parathyroid hormone-dependent mechanism.

The acute effects of chlorothiazide (CTZ) on total (TSCA) and ionized (SCA-plus 2) serum calcium concentrations were studied in three groups of people: (a) eight subjects with normal parathyroid function; (b) six patients with hypoparathyroidism; and (c) two patients with hyperparathyroidism. Most subjects were studied on four occasions; at least 3 days intervened between studies on an individu...

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a comparison of linguistic and pragmatic knowledge: a case of iranian learners of english

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ژورنال

عنوان ژورنال: Journal of the American Society of Nephrology

سال: 1996

ISSN: 1046-6673,1533-3450

DOI: 10.1681/asn.v73497